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Impactful malaria science, and the trailblazers leading the fight. A podcast from the Johns Hopkins Malaria Research Institute.

Nov 27, 2023

An old malaria drug gets a new formulation. But how good is it – and will it drive resistance?

In this podcast, we ask:

  • What are the limitations of current malaria vaccines?
  • What is the concept of long-acting injectable (LAI) drugs?
  • What are the clinical and chemical properties of atovaquone that make it suitable...


Nov 14, 2023

How ‘chemical vaccines’ could offer long-term protection against malaria in endemic areas, and combat the problems of dosing and drug resistance.

Transcript

Drugs used to prevent and treat malaria are vital tools in the malaria toolkit – but they aren’t perfect. When used to prevent malaria, people must remember...


Oct 23, 2023

Drug efficacy studies are revealing the spatial distribution of mutations causing artemisinin resistance - and it all starts with a drop of blood.

In this podcast, we ask:

  • What is artemisinin resistance?
  • What are some of the key molecular markers underpinning it?
  • How can we overcome it?

With Didier Ménard, Director...


Oct 9, 2023

Researchers examine the rise of artemisinin drug resistance in Eritrea - and search for its genetic basis.

Transcript

Artemisinin – a key antimalarial drug – and other drugs derived from it, are fast losing their effectiveness across South East Asia and increasingly in Africa, too. To investigate this, researchers...


Sep 25, 2023

In 1951, malaria was eliminated from the US. But just this past summer, the parasite that causes the disease has re-infected local mosquitoes and caused a handful of cases of malaria in three US states.

In this interview podcast, we ask:

  • What should we make of these cases?
  • Is the public possibly at risk of...